As researchers embrace more complex cellular models, high-content analysis brings new opportunities and challenges to drug discovery.

Welcome to the Weekly Rundown where the DDN editors cover this week’s top biotech and pharma news.

Twenty years ago, drug discovery ran on a simple script of screening compounds and hoping for a hit. This exclusive ebook, ...

Alzheimer’s disease often overlaps with other causes of cognitive decline. A new proteomics project aims to untangle that ...

Traditional animal models remain an important part of preclinical research, but species differences can limit translation of ...

From AI agents to cell therapy to Alzheimer’s drug pipelines, this issue follows the same problem across three fields:what it takes to turn something that works once into something that works at scale ...

Priyom Bose earned her Ph.D. in Plant Biology and Biotechnology from the University of Madras, India, in 2019 before ...

Antibody discovery is becoming less about finding the strongest binder and more about finding molecules that can survive the journey to the clinic.

Injectable peptide drugs have transformed treatment for type 2 diabetes, obesity, cardiovascular disease, and inflammatory conditions, yet their route of administration imposes a daily or weekly ...

But NRTIs are known to have serious toxicities, so Ambati’s team created new chemical derivatives called kamuvudines that ...

New findings slowed tumor growth in a mouse model of triple-negative breast cancer, offering a new template for RNA drug ...

A win for autoimmune disease, a set back for Alzheimer’s disease, an FDA backing for a multi-cancer blood test, and more led the news this week.