Sam Farmer makes his picks and score predictions for Week 16 of the NFL season, with the Rams sweeping the Seahawks and the Broncos extending their winning streak.

A look at who is predicted to lead the NFL in receptions in Week 16, plus accompanying player prop betting odds.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 52-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

The wear and tear of an NFL season can take its toll on stars, leaving fantasy managers to scramble for a replacement, searching far and wide (and sometimes deep) at certain positions to find a hidden gem who can earn them enough points to achieve victory.

All odds referenced are courtesy of BetMGM as of publish time.

Jacksonville Jaguars quarterback Trevor Lawrence (16) scores a touchdown on a keeper during the first quarter of an NFL football matchup at EverBank Stadium, Sunday, Dec. 14, 2025, in Jacksonville, Fla.