EurekAlert!

Common mutations prevalent in low-grade ovarian cancers

Mutations in the growth regulatory genes BRAF and KRAS appear to be associated with the development of low-grade ovarian cancer but not of aggressive high-grade ovarian cancer, according to a study in ...

Childhood leukemia aggressiveness depends on timing of genetic mutation, research reveals

A team of researchers at the Icahn School of Medicine at Mount Sinai has uncovered why children with the same ...
ascopubs.org

Germ-line BRCA mutations in high-grade ovarian cancer: A case for routine BRCA mutation screening after a diagnosis of invasive ovarian cancer.

Sequence specific effects on DNA and cell damage with the PARP inhibitor olaparib (AZD2281) and carboplatin. This is an ASCO Meeting Abstract from the 2011 ASCO Annual Meeting I. This abstract does ...
ascopubs.org

Relationship between IDH1 mutation status and magnetic resonance imaging features in WHO grade II and III oligodendroglial tumors.

The impact of bevacizumab on the occurrence and recurrence of intracranial brain metastases in non-small cell lung cancer (NSCLC) patients. This is an ASCO Meeting Abstract from the 2012 ASCO Annual ...
News Medical

Research reveals new treatment avenue for pediatric high grade gliomas harboring a genetic mutation

Researchers at the University of Michigan Rogel Cancer Center have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat ...
Targeted Oncology

Zanubrutinib/Venetoclax Continues to Impress in Treatment-Naive CLL/SLL

Zanubrutinib and venetoclax combination shows an 87% 36-month PFS rate in CLL/SLL patients, regardless of del (17p)/TP53 or IGHV status. The SEQUOIA trial demonstrates durable minimal residual disease ...