CHAMPAIGN, Ill. — Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its ...

Medically reviewed by Stella Bard, MD Key Takeaways Yoga might boost GABA in the brain. Benzodiazepines can increase the ...

GABA receptors, long recognised principally for their role in modulating neuronal excitability within the central nervous system, are now emerging as pivotal regulators of immune function. These ...

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability. The cause, which has been well-studied, is the loss of fragile X mental retardation protein (FMRP)—a genetic ...

People with the inherited disorder myotonic dystrophy (DM) often experience excessive daytime sleepiness and fatigue, as well as altered responses to anesthetics that can put them at risk for ...

F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have prepared and tested cyclopenta-thieno-diazepine derivatives acting as GABA-A receptor subunit α2β2γ1 positive allosteric modulators (PAMs). As ...

Respirerx Pharmaceuticals Inc.’s lead GABA-A receptor potentiator, KRM-II-81, has advanced to the next level of evaluation within the National Institutes of Health (NIH) HEAL Initiative Preclinical ...

It may be possible to reduce the severity of COVID-19 symptoms with an inexpensive amino acid that could open up new treatment options for patients. GABA is a natural molecule that is available ...

Tweaking the numbers of receptors in a key brain area changes the daily rhythms of rest and wake in mice. In humans and other animals, signals from a central circadian clock in the brain generate the ...